Why Celebrities Should Not Take Their Role Too Seriously

We all know that in today’s popular culture and trends that we have celebrities who are expected to fulfil certain things to satisfy audience at large without actually showing true talent behind them. The question is, why? People have wired this new trait into the human race. They want to be the number one at everything, no matter what it is. this is actually a trait that has been around for as long as human evolution has existed, but with the emergence of language and technology, we can rebuild new traits.
Male celebrities try to compete and female celebrities are constantly at the vanity. So what happens when we have some kind of overlap–the question I asked before, why is it okay for girls to be tomboys, but not okay for boys to be sissies? Let’s take Justin Biever, for instance. He may act all tough and manipulative, and people have disputed his gender and sexual identity because of the way he sang when he was little, and sometimes because of the way he sings now. So, what happened to the real Justin? His masculinity is slowly being taken away, and he is using his tough-guy act to cover it up. Take a look at this scenario a friend provided me with.
One day he went to the United Kingdom and while he was there, he fainted on-stage, so he went to a hospital. Well, when he got out of the hospital, he went back to his hotel to play with his Xbox or whatever, causing him to be not one, not two, but three hours late to a concert! For it must be understood that someone of his celebrity status is often paid to do a job, and with his fans being little kids or young teens, they have curfews and have school the next day. And also parents have to work hard, sometimes doing so many jobs just to afford those ridiculously overpriced tickets. Meanwhile, he gets paid millions upon millions of dollars while the hard working man barely makes enough for himself let alone for his overly-obsessed daughter with even more overly-obsessed teen heartthrob fantacies. Anyway, most people instead of waiting around for him to show up just get up and leave. Without so much as even giving an apology to those who were practically waiting around all hours of the night for him to show up to sing a few songs, he just comes in, kind of performs one or two songs and just goes home. He tries to tweet about how sorry he is on twitter so as to make people believe it’s all water under the bridge, when in all reality it most certainly isn’t. That’s one reason why I think he’s a sissy boy. He’s getting all the opportunities that people with true talent should be getting! He’s making it hard for real singers to become discovered! Now let us get onto the most obvious reason why Justin Bieber is an example of a sissy boy. Okay, so after that disastrous concert where he was booed for showing up late and rightfully so, he goes back to his hotel to crash for the night, or does he? The answer to that question, the world may never know. However, what the world certainly does know is that the next day, as he’s exiting the hotel, lo and behold. There are papparazzi! So they say a few words to him, he’s got his big fat body guards that are probably in all reality just as much, if not more of sissies than he is. So he tells the guys to move out of the way, and as a result a fight begins, all because some guy said a few words that the body guard didn’t like. The photographer wasn’t even directing his words at Bieber, and it was only after Bieber jumped out of the car did the his words become directed at Bieber. So Justin decides to play tough by saying he’ll beat the crap out of the guy who said whatever to set Justin and his crew off, and lo and behold, those body guards are basically carrying him back into the car! So basically instead of the body guards letting Justin put his money where his mouth is to prove how much of a man he really is, or rather, the lack of a man he really is, these body guards of his are yet again not only babying and spoiling him, but are perpetuating his downward spyrol. And that is why Justin is now in the lion’s den, and why Justin Bieber is a sissy.
I don’t know much about this interpretation. To be honest, this is beyond my scope of comprehension, so I cannot make any comments of my own. What i can say is based on what I have conducted when I researched Justin. Perhaps there are some missing points that, when added would give a person more of a mental picture as to why Justin is more of a sissy than we realise.
People who are cowards try to use fear as their biggest weapon, and that’s what most bullies do. Of course the best thing you can do is laugh it off or use verbal judo to intimidate the bully. They say if you fight back you are only giving the bully more power because they are wanting to feed on the feedback. If the bully gets no feedback they will get tired. Lois Lowry wrote in ‘Son’ where the trade master has to watch the outcome of his evil powers. If he makes a person incapable of walking, he’ll watch that person struggle to walk and it’ll be like some kind of food to this creature. If he is unable to see this, he’ll get hungrier and hungrier because he needs to feed on this power. The same goes for bullies. They want results to give them more energy.
I have never appreciated how guys use their clever tactics to impress the girls by acting all tough and or girly. That’s not real and honest mating. How do other animals mate? How do humans in other parts of the world mate? I’ll cover that in another post.

My newly-found phreaking Abilities

Ever since I was about seven or eight years old, I learnt how to distinguish the sound of each note, hence how I developed my absolute pitch. However, I discovered that I could apply this perfect pitch to not just music, but also things like using the telephone, recognise certain textures of sound when I dial the telephone, and knew when I was calling a fax machine or dialup system. At the time, I knew that these were tones that a person could associate with these things. When I started getting more technical in later years, I learned that computers used tones in various forms of sine wave frequencies to communicate to each other mathematically across long distances. These tones also included different types of noise as well. That brings me to something I just discovered. Up to this point, I did not know that the emergency alert systems found on television and radio used tones to send encoded messages across the network, yet when I heard the tones I associated them with an emergency message. I did a bit of research and learnt that the series of tones I was hearing was called the specific area of message encoding, or SAME.

As blind people, we tend to be more aware of our surroundings, with our third or mind’s eye. We are able to see and hear beyond, like in ‘The Giver’. This doesn’t mean that we cannot see and or hear physically, but it just means we are able to view the world differently. I have been able to recognise speech synthesisers that you would normally find in screen readers on places like the public city bus, in movies, the ATM, and other keosks. Of course, this doesn’t mean that blind people are the only ones who know about it, for certainly there must be a number of sighted people who know about these things, only they are not visible to the general public. I know a number of amateur radio operators, and as mentioned in my post, blind people seem to develop their own culture that is devoted to the mannerism associated with radio communications. This leaves outsiders who cannot conform to the culture to be overwhelmed because we cannot understand their close-mindedness.

I looked into the phantom flute phenomenon, where if you play two flutes in the high ranges, you will often hear a third flute that is not present. This is due to the resultant (sum of two frequencies or difference of two frequencies) that I was picking up. As a prospective piano tuner, I had to know what these were and how they would get in the way when I was tuning really high strings. The same applies for dual-tone multi-frequency or DTMF tones. When you dial a number or letter, two given frequencies that are predetermine create a unique texture that allows a person to know what is being dialed. In FBI and other forms of criminal investigation, people like us can listen to numbers being dialed so we can track the numbers of the party the caller is calling. This same thing goes for people who are incapable of measuring heart and breathing rate, save for the equipment they need.

When I learned how to differentiate beatings, i also learnt how to calculate frequencies that humans cannot hear based on how they feel. I could mention in a job interview that I can calculate a person’s heart rate, or a tremor based on my knowledge and muscle memory. I can calculate how fast a fly’s wing is buzzing while scientists had to use expensive equipment to do that. It’s a shame, because they could have matched the tones using a free programme like audacity and the recording of the insect’s wings.

When I was making these discoveries, I knew I wanted to try out a facsimile machine, and use dialup, despite the fact that people said those things were going out of date and that dialup was slow. It wasn’t because of the obvious that I wanted to use these systems, but it was because i was fascinated by the sounds it made when it communicated across the telephone line. I was wondering if some day in the future transhumans will be able to decode messages like morse code used in amateur radio in a natural sense, without using implanted devices. I got inspired by this idea when someone told me that scientists would be able to upload brain waves that escaped from your ears into a database. They would burn those brain waves onto a CD, which holds some form of music. Let’s say you are dancing. They would be able to record how your brain behaves when you dance. If they could copy that into a computer and replay it back in a room full of people, then everyone would start dancing because their brains would be decoding the brain waves.

So, I have met other blind people who shared this same passion of mine and we believe that if more people were interested in a certain way, not to the point where we know all about it, but to a certain extent, we could change the world in getting more people to pay attention more closely. What do you all think? I think we can learn how to be more aware of our surroundings if we just stop going into our iWorld environment and get out into the real world, because the iWorld is for people who are close-minded and selfish and the real world is for people who really care. We need to keep onto empathy and compassion.

Electrolysis Hair Removal

Ever since I began to look at the art of electrolysis as a vocational career, I have run into several controversial marketing and sales issues regarding home systems that do not work and how much discipline a person must possess to be able to treat themselves efficiently and expertly. I decided to put in my own views on this matters and focus on all sides to encompass all the problems these web sites have on consumers.
Last summer of 2013, I heard about a small, battery-operated gismo called the One Touch Clean and Easy Deluxe Home Electrolysis system. This page explains about what the machine does. As a blind person, I discovered that no where on the manual or web site it says vision is required to use the product. I can say from experience that you can feel the areas you are treating. However, because the world consists mainly of sighted individuals, it makes sense to use your vision more and pretend that visual deprivation will not make a difference. It does make a difference, because you can pay attention to detail using your tactile and auditory senses.

Another reason why home electrolysis is not recommended is because of lack in skill.

While this may be true in most cases, I believe that in order for a prospective professional electrologist to be successful, they must first understand how the treatment works. If they choose, they can treat themselves. However, in our society, self-image and integrity are important than the will to care for others. That’s why people lack discipline to really learn the procedure. Lack of skill can make treatment more painful if not done properly. Again, this might be true, but this is because this person is not willing or motivated to taking the time to really do the job well.

Whilst self-treatment is an option, it can pose as a danger to the electrology profession because less people are paying to have it done for them, and the fact that people have more control over their pain threshold than if it was done professionally. Again, I think there needs to be a balance, such as using sensation transmission to bond the client and professional together via use of electrodes on the brain, or using nitrous oxide and oxygen to relax the client during the procedure. I often find myself listening to music and or an audiobook while I undergo the treatment, as it helps me concentrate more on those than on the stinging sensation I get each time. Again, electrologists who are capable of treating themselves are highly encouraged to join the electrology field so that they can pay back in ways money can’t do.

Five months later, I came across a system called the <a href="http://www.vector-electrolysis.com/'Vector Professional Electrolysis System Trademark, which uses lethal voltages to destroy hair with tweezers and a conductivity gel. However, I’ve been checking on Hair Facts’s hair removal section and things to avoid. I should point out that the information is out of date, as this happened in 2001. Now it is 2014. A lot has changed since then.

I did some comparison between the Deluxe manual and Vector User Guide.

Here are a few examples.

  • Both the One Touch manual and Vector User Guide indicate that the products must be used by people eighteen and older, and to keep away from children.
  • The Vector User Guide explains the procedure of how hair removal works using chemical reactions. The One Touch manual does not explain this very clearly.
  • The Vector Electrolysis web site indicates that battery-operated devices do not emit the kind of current that is found on professional systems. The One Touch system is battery-operated, and is a whole lot cheaper than the Vector system. Someone once stated that the cheaper the system, the high chances is that it will work than those that are more expensive.
  • The One Touch manual references warranty up to a year for any damage. The Vector User Guide does not. The only place I have seen this for the Vector is on the Active Forever site.
  • On the Vector Electrolysis web site, there are consistent misspellings of the words then and than, and in a few instances, the word electrologist is written as electrolygist. On their contact form, the letter N is missing in the word functional therefore making it fuctional
  • The One Touch manual makes a list of conditions in which a user must not use this product. In the case of the Vector User Guide, the only reference there is to such conditions are heart problems and use of a pacemaker, but everything else has been omitted. This is because the device uses a grounding electrode pad, which the One Touch does not use.
  • With any kind of current, it makes sense that the more intense the current is, the less time is required to remove the hair. The Vector User Guide makes note of this, but the One Touch Deluxe system does not, but it does make a vague reference to this.
  • The One Touch System emits a five-second tone with several unusual harmonics, indicating that the current is flowing. After five seconds, if the circuit is still complete, it will continue to beep for another five seconds. This is not referenced in the manual. I usually count three five-second beeps before I remove the probe.
  • There has not been any clinical trials or scientific publications stating that hair can conduct electricity when applied with the gel. This raises one question. Why? Can scientists not afford to open such a study where professionals and consumers can participate in clinical trials, and if they are as effective as claimed, then they can be safe?
  • The Vector User Guide recommends that you wax or tweeze hair before the actual treatment itself, as this makes the underlying environment to be highly moist. The One Touch manual does not make such an indication.
  • The company that makes the Vector system says that they have a needle, which requires a license to purchase. However, they do not recommend using a needle, as this can increase the risk for infection and also increase the likelihood of a person being shocked.
  • A reviewer of this product said that the electric tweezers don’t grasp the hair well, thereby making it nearly impossible to treat, but they believe it worked for them.
  • The Vector User Guide makes a note of when to treat hair during which growth phase. The One Touch manual does not.
  • All in all, each company is trying to convince you to buy their products to make their own profit, which is common in capitalism.

Having said all that, there is a concern that the public does not clearly know how to distinguish fact from fiction or quackery.

Companies are so good at convincing people in making them believe that their products work well when they have not the proof, other than to make redundant statements throughout their web site. Let’s take this a little bit further.
As stated above, no scientists have studied these products. All companies had to do was put the United States Food and Drug Administration logo based on junk or sound science. As an alternative, we have become too dependent on the government, and as a conspiracy theorist, I believe the public is ignorant about how to overcome these issues. It is time for newer and more holistic measures to be taken. We should not be suing companies for things that they have no proof over. If you want to see proof, a scientific study must be conducted between a chemist, a physicist and an electrical engineer, along with professional and amateur electrologists to really make sure the product does work for all kinds of skins and hair contrasts. If not, scientists can use genetic modification to close the hair pores and change the skin type. That itself is another matter, as surgical hair removal is not yet being performed except for hair transplants.

For my review of the One Touch Deluxe System on YouTube in honour of the Blind LGBTIQA Pride International, I discussed some of the things the system could do, and how a blind person could work with this system.


In conclusion, I think it is up for the consumer to experiment which systems work well, even though they might be putting themselves at an opportunity cost. If you have any questions, comments or suggestions, I’d be glad to address any concerns you may have. I may also update this post if I find more information that might be useful.

Using Augmented Reality as a Real-Life Test for Prospective Transgender Individuals

It’s been a month since my previous post, but during that time I’ve been working on my story and that has been going well. I am going to spend more time here writing it as I curl up on the couch in the den with a pair of headphones hooked up to my TV, with earbuds underneath so I can listen to my computer at the same time.

For those of you who don’t know what I’m talking about, we’ve been hit by heavy snow and winds.

Phil must have saw his shadow after popping up from the ground. Coincidentally, Superbowl XLVIII fell on this very same day. Of course, he made this prediction at seven in the morning. This means we’ll have six or more weeks of winter. I’m not sure how many of you are superstitious, but it’s kind of interesting nonetheless. Anyhow, I digress, so I’ll go ahead and get down to business.

While I was writing my story and collecting resources to cight, I noticed that a lot of people, especially teenagers and preadolescents were coming out as transgender. The number of transsexuals have been rising, and no one knows why. Is it due to prevalence in popular culture? This has lead me to suspect that many say they are transgendered, but when they begin the actual treatment, they would regret their changes or any irreversible effects that were caused by medical interventions. As an optimist in the science of transhumanism, I believe the day will come when nothing will be permanent any more. There’s been advances in speculative stories about using nano, pico, and femtotechnology that would physically change your body, so that stem cells would not be needed to regrow the organs and transplant them. In some stories the stem cells only work with male-to-females, all the way down to the chromosomes, but if it were to be applied to female-to-males, the procedure would kill them because the Y-chromosomes would not be able to be converted from one of the X’s. However, many of these stories do not have bibliographical references to let the reader know that this is true. I have been looking at these things whilst writing my own. I also learned about medically-induced comas that could be used if the body changes too fast and the patient is in great pain. That would be like Rip Van Winkle. While the brain is deeply unconscious, the body changes. When they wake up, they would feel as if they were reborn, which in some cases is true. In other circumstances, the body changes while the patient is conscious and alert. In these situations, the patient’s mind and thinking patterns have time to synchronise with the body, but a comatosed patient would have to wait until after they changed. The question then becomes, are they really sure they want to be the person they dreamed of being?

Let’s think about the kinds of motivations that make people want to change. Crossdressers who say they want to change from male to female say that their bodies sexualise females before their minds do, and they end up giving into these arousals. Some feel that females are dominating their society, and if they feel they are more dominant in certain areas they feel they would be one of those people to break the stereotype associated with masculism. A person who has prolonged persistence that they are in the wrong body has the proper thinking patterns as a female, so the changes will usually have little or no consequence on the patient than if it was done with crossdressers. For these reasons, the Harry Benjamin Standards of Care state that a prospective postoperative transsexual should take a certain amount of time taking the real-life experience. This is where the person must live full time as their preferred gender role and learn how to deal with experiences as they start to build their self-assurance. A lot of parents feel that their children are making a big mistake because they fear that if they change their mind, there would be no turning back. As stated in a story I read recently Living Transgender has lots of costs, not just in finance but in many other things. There are a lot of problems in being the person they are inside. For instance, do women who want to be men feel they want to change just because they want to avoid rape and abuse, or do they feel that way ever since their infant personalities have been developed? i know several people who have successfully transitioned without plastic surgery, as stated in my story. In fact, people implant technology just to treat diseased tissue, but looking at the bioethics, do we change healthy tissue just for aesthetic and cosmetic purposes? What if we had future technology that could use the healthy tissue as a host to change the structure without actually having it removed.

Let’s look at what someone has written about what they feel is not necessary from a real-life experience. Here’s what one person has posted. I have been giving this some thought. In my story, I used the concept of oneirology as a way to help the protagonist decide if they really want to be female before they actually get there. As you all know, living in the opposite sex has a completely different, if not similar, set of sensations, as well as brain structure to allow more emotions to flow through. What if we could interveen by using technology to help influence a person’s dream, give them a virtual reality experience that uses the person’s memories, sort of as an age regression technique to build the foundations to a memory the person will never forget. Would it help a prospective transsexual say, ‘No, I don’t want to change. It’s too overwhelming and confusing for me’? If that was the case, everyone would save a lot of time than if they have said that after their sex-reassignment surgery.

Although I may be jumping too far ahead into the future, there is no doubt that this could benefit thousands of people, but still there is a strong opposition and controversy over these things. The question is, why is there such dispute? It’s mainly because of religion that dominates society, and the ignorance people have about science, and things people see in science-fiction media in popular culture, which many is not true. As fascinating as these techniques can be, a lot of it remains questionable. What would we use to control what a person dreams? Do we use mind-uploading and mind-reading technology to manipulate someone’s memories, or do we use hypnosis and our brains’ ability to recreate sensations based on similar sensations it has recorded?

Having said that, I hope that we can get there sooner than later, as I know there are people anxious to transition in a natural and biological method so that they can continue reproducing as before. Let’s continue to help educate the people we talk to in hopes of eliminating stigma surrounding these issues.

Selective Service is one of the Worst And Most Sexist Discriminations against Men

I haven’t been posting a lot since I’ve been writing my book, but I thought I would inform you about the injustice of our American culture.Selective Service is one of the Worst And Most Sexist Discriminations against Men.
I’m not sure what new movements have been made since this article was published, but if there’s anything new feel free to share them with me.

Things to be Covered in 2014

Happy New Year to all who are following. This year, I hope to cover a little over what I went over last year, and discuss some aspects of how transhumanism can have an impact with our environment and cultures so we can figure out how to correct mistakes, like HIV and AIDS, diabetes, cancers, creating and taking down cell receptors responsible for addiction and more.
So, let’s begin. I have been thinking about how people of younger generations don’t get the meaning of respect, that instead of evolving we are (d)evolving because people are out for image to satisfy their own flesh, and not one another. Of course, John Locke pointed that out several hundred years ago, but it has become more wide-spread, just like strokes are becoming more common in teenagers, something that usually happened to old people, which I will cover later. Now, I have done plenty of scientific investigation as to why these things happens. It turns out that many people have rewired their genetic coding that produces neurosteroids and such that makes proper mental development. It is not only the fact that we are capable of rewriting our genes, but our environment and culture plays an influence, like how much repetition and nurture we have had, and even as babies, how much we have been breastfed. It also depends on how stable your families were, how much positivity you have received, and how personal you have taken negative criticism. All of these play a role on how your thought patterns turn out in the end. Some experience anxiety problems, depression, irritability, and more. I have been trying to look at ways to induce such problems and then get rid of them so we can widen our world view. I have heard that people with too much dopamine gives them illusions like hearing voices of people they talk to a lot among other things. I have never heard voices in my life, but I would be interested in knowing of a way to ingest something that will do it temporarily. Now, as exciting as all this might sound, I want to remind all of you that these scientific findings can help enrich our society so that we wouldn’t have ignorant people questioning those in the minority. Many just tell you the obvious, but hardly don’t get into depth.
Ever since I started paying attention to the news full-time in 2008, I found it quite stupid that we have prisons and we spend time sending criminals to be locked for a costly sum, and then killing them if they do not reform. Many people think it would be dystopian or immoral to send these criminals to science labs to have their brains altered, their body chemistry permanently altered using engineering techniques, and possibly a technique to induce total amnaesia-like characteristics. In a way, you are rewriting their personality. You are using science to turn a bad guy into a good citizen. However, something motivates a person from killing another person. I was wondering, could it be possible to restore a dead person to life if we could salvage their DNA? Their personalities may be the same as the old person, but they wouldn’t have the same memories. They may look the same to you, but something will remind you that it is not the exact person, because they would have to learn everything. They aren’t re-learning, since this is a clone of the person who was murdered. I have asked people from varying religions and many think it is due to choice which one has the ability to make. In dystopian societies, people are prevented from making their own choices so that they would turn out to do good in the community. I think we all have the freedom to make our own choices as long as we have the proper balance in our system, in our bodies, and in everything.
How does a person manage to be motivated to committing a crime when they take drugs that physically addicts them, or as we know, getting them high? Does it cause the brain to mix scenarios in their minds, and make the person attempt those scenarios to see what goes on? Many universities have been looking at the biological and physiological causes of physical addiction to see if we could come up with a cure. In cases where nicotine is inhaled or applied using a skin patch, scientists were trying to create new cell receptors to see if they could stimulate the reward system of the brain. Many people describe it as having a feeling as if something exciting was about to happen (this is how yellow and white light makes us feel). People also say that babies are addicted because of those cell receptors being mutated into their genes, but that only gives me one question. How will that baby know, when old enough that they are addicted if they have never taken that drug before? Will it feel like having this extra sense that you are hungry, but no matter how much you eat or get enough air, there is something that you can’t seem to get unless you stimulate those receptors or destroy them all at once?
Ever since I wrote up that short article on vocal analysis, I came up across something very interesting called the castrato voice. When I analysed the harmonics of these voices, they came out with very unique characteristics that make them sound neither male or female. They have their own way in terms of how they sound. They underwent a lot of training once they have been castrated before puberty, but they grew exceedingly tall, pale-skinned, and had no muscular build at all, and many lost bone density. They weren’t trans because they didn’t undergo hormone replacement therapy, they were just prevented from developing secondary sex characteristics. In the GLBTQIA community, within the arts encyclopedia, they were called the castrati, Italian for castrated in plural. Scientists have been looking at how to recreate the once dead voice into a live voice by using what we know about sound.
A few days ago, I came across some naturopathic ways of treating things like thyroid problems that are sometimes the cause of depression and anxiety, metabolism problems and such, and how we can treat them using amino acids rather than medication that do more harm than good. I have also been trying to see if there were naturopathic neurologists working on a cure to low and high-grade haemorrhages and seizures. That brings me to talking about the split-brain patient. When a person has no way of connecting the two halves of the brains together via the corpus callosum, they end up having unusual visual reactions, and many can draw shapes with each hand independently. Sometimes, people are startled to see that their hand, the one not intended to be used, to move and grab the object. Is there more of a humane way of cutting off the electricity between the regions and the two halves without using surgery? I thought that if we could attach these to sighted people, we could temporarily deprive them of vision and visual memory. Since the year 2009, it has been discovered that we have done a lot of misdiagnosing on people whom we thought were in a coma, but who actually turned out to be fully-conscious and completely paralysed and unable to respond to any kind of stimuli, yet their brain works very well and is still able to perceive and reason. What if a brain transplant could give them deparalysis?
How I plan to do deep-brained stimulation without cutting into the brain and implanting electrodes is going to be the hard part, but when I researched, I discovered I could look at several different inventions and see if I can apply physics to these. We know that the brain uses glucose for fuel. So what if we charged this radioactive fuel with a positive charge, and once the body has been polarised, then all we need to do is discharge it in the right part of the brain. We are fortunate that outer-brain stimulation can be achieved because the electricity goes through the scalp and skull. That’s why we have devices like the neuron-engineering and transcranial magnetic stimulation device, which I think some day will help blind people how to see. In a science-fiction story, it was suggested that if we used this energy, we could figure out if the mind can be altered and carried across the electricity between a body that has been negatively charged and vice versa. The problem is that the mind is not just stored into one part of the brain. The mind is distributed everywhere, which is why mind-uploading would be hard to do, even body-swapping without any form of transplantation. So, what gives parts of the brain responsible for identity?
Understanding Norrie Disease: I have written this next part to see if I could explore some of the rare diseases that make people blind that are among many other rare diseases, so this is just one of such that I plan to write about.
We all know Norrie Disease is a rare genetic defect, but what actually causes it, and how is it present? What treatment and cures are currently being worked on? You will get to know how this disease works once you have an understanding of how genes work.
What are genes? Genes are a set of instructions, composed of DNA and RNA sequences, sort of like the strip of a magnetic strip used by computers to obey certain tasks. Better yet, a gene is like a set of blueprints to build a house. It provides detailled instructions on what the body should produce, when to produce and develop, how to produce, etc. Scientists have begun to understand the aspects involved in eugenics, which is to isolate one good trait over bad ones. Traits are characteristics based on several kinds of genes. There are physical traits such as build, hair and eye colour, body fat storage, bone structures, melanim production, hormone and neurotransmitor production, and many, many more. There are also traits devoted to the brain, called mental (left hemisphere) and emotional )right hemisphere) traits. This includes things like how much hormones you are making, how many neurotransmitors you have present, among many more such as described in the physical traits. Note that these traits can be modified to some extent, but some require nerve stimulation or cell receptors which may be absent if the genes for these are not present. These things are what determines a person’s outlook in life, such as being smart, dumb, and the list goes on.
What happens in Norrie Disease? Typically, this gene attacks the majority of XY chromosomes but rarely XX chromosomes, which is why males are definitely going to have it than females. The gene’s origin begins with a mutation, such as a virus or infection, though the former has shown that these genes can be affected. When Norrie is present, it begins to start damaging cells of varying types in the eyes, and nerve cells in the ears, and in some cases, the brain is affected. Norrie also prevents development of eye functionality during prenatal development, which is why many patients are born without knowing what it is like to see.
How was Norrie discovered? An ophthalmologist from Denmark started studying seven different people from the same family, and each of these people were male, and were past descendants from the first generation. The disease was named after another famous ophthalmologist named Gordon Norrie, who was recognised for his great achievement in working with the blind during the mid to late nineteenth century and into the twentieth.
Causes and Effects of the Gene: Norrie is caused by several mutations found in genes called NDP, located in Xp11.4, and its ID number is 4693). Causes of mutation vary greatly. For future reference, all genes are binary, meaning the gene is dominant or recessive. This means you could carry the genetic coding, you could be mutated with this gene, or both. To illustrate this example, use a Punnett Square that can show you which are dominant and which are recessive. Capital letters indicate positive and lower-case letters indicate negative. In a Punnett Square, there are four letters, sometimes distributed equally, sometimes distributed based on chromosomes, and sometimes distributed by a mix of all of these. In order to understand this concept further, you must know what a phenotype, genotype, hybrid, purebred, pedigree, and family tree is. Better yet, take a genetics-101 course for a non-technical explanation on these terms and their etymologies. It helps if you understand the root and stem words of each term, for this is how they have been coined.
Please note: A mutation is when a given sequence or set of instructions is left unfinished. Take this string of letters, don’t worry about what they mean just yet. A turns into T, T into A, G into C, and C into G. In the second stage, A turns into U, T into A, and C G remain the same. U becomes A, and T becomes A. A very common mutation is TAG, which is usually found at the beginning of a sequence. In genetics terminology, we call this transcription and translation. We say transcription because the gene is being converted from DNA to RNA. Once that’s done, it needs to be translated to form a protein. In other words, mutations finish their job prematurely, leaving the cells affected. This is why people can be mutated to eating certain proteins from products that have them as well as how things are digested like gluten. We will discuss these later on.
What happens when Norrie is present and the gene is mutated? To understand this concept, you must understand how proteins work. We all know that meats and eggs have proteins. in fact, anything that can walk, run, swim and fly has protein. Proteins is what DNA and RNA are composed of. DNA stands for desoxirribonucleicacid, and RNA, ribonucleic acid, is what people use to match characteristics, such as determining which person was responsible in a crime. All of these proteins have a three-dimensional shape, and can be demonstrated using molecular models and high-powered microscope slides. The shape of a DNA is like a spiraling latter with its backbones curving to form a double-helix. The rums of the latters contain four distinct articles, one set on every rum. This DNA can be found anywhere throughout the body, such as skin, hair, blood, and any kind of body fluid.
In Norrie Disease, the mutated gene called NDP, instructs a protein called norrin how to set its foundation. Norrin is responsible for the development of the structures that make up the eyes. As you know, norrin consists of several amino acids that give it its shape. When the NDP gene is mutated, however, this protein doesn’t form properly and becomes mis-folded, giving it an unusual shape. Think about a lopsided house or something of that nature. When this happens the protein is unable to function, and therefore the eyes are unable to develop properly.
Other things Norrie Disease can affect include hearing, balance, excretion problems, and mental development disorders. It is believed that norrin is responsible for supplying blood flow to the retinas, and tissues of the inner ear. This is why it is likekly that Norrie victims will experience hearing loss, because hair cells in the cochlea will eventually die out. There are immature cells forming in the back of the eye, which causes degeneration of important cells and blood vessels. Norrin abnormalities can also affect which parts of the brain are developed, such as neurosteroids and neurotransmitors. However, it should be taken into account that individuals with prelingual deafness are unable to communicate, and for this -reason many blame mental disorders when in fact that is not the case.
Severity of the disease is variant on how many amino acids have been mutated and their location. Few mutations ensures that the person will not be as affected than if a person had widespread complications. It has been documented that males with Norrie disease have behavioural problems, but at this time there are too many biological factors to determine the causes of such findings.
Futuristic Outlook and Testing: As of 2014, little research has been conducted to find better methods of testing the molecular structure and mutation of the genes, and although they are accurate, as far as we know no attempt was made to replace the mutated gene with a healthy one to see if the rewritten gene would correct the protein’s structure. If the protein structure were to be corrected, would the eye structures start developing again, or would we need to turn our attention to finding the right growth factors to get stem cells to grow? Studies have shown that prolonged exposure to how we interact with our environment based on how we socialise and how we identify with our culture gets written into our genetic coding, but there are some genes, such as the NDP that cannot be rewritten once it has been mutated. Current research shows that once a gene has been modified in an organism, that organism usually develops negative side effects, cancer being one of them. We still don’t yet know why this is. Research to sensory substitution and augmentation for people blind at birth still continues, despite the controversy found in the blind community. This may be relevant to how cochlear implants are being contradicted in the deaf culture. It is hoped that a creation of a new virus could reverse the gene’s mutation without leaving harmful side effects in the future.
For further information about Norrie, Go to: http://www.norriedisease.org/
Lastly, why do people not use anaesthetics like nitrous oxide when undergoing cosmetic enhancements, like piercings and tattooing? I don’t see any reason they should, so why shouldn’t they? It is hoped that regrowing tissue with stem cells and right growth factors can replace plastic surgery.

A Reblog Regarding a List of Things to Do Before You are Ready to Marry

The following post received 85% criticism and 15% positivity. However, I seek to find alternatives to these two sides or, finding a third side in this post.

23 Things To Do Instead Of Getting Engaged Before You’re 23.

Just because the author of this post said you have to do these things, everyone comes from different backgrounds, so everyone will interpret these things in their own way. However, there are some things related to it that could benefit a person who is not knowledgeable about society or who are looking for a change in the social system of today. So, everything stated in this post can be contradicted and can have exceptions.
To succeed in this life, balance is the key to success.